I haven't watched much of the anime (sadly).
No she is not, this story arc was left out completely, mind you I forgot in the whole timeline where she shows up.
So for now no she is not in the anime
That is a terrible shame. San is one of my favourite characters in R + V, mainly due to her uniqueness and badassery (anyone who flew in front of Alucards face with a note book deserves my respect). Hopefully she appears soon in the anime.
Sadly, she's not :(